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Theta Hat Statistical Consultants LLC.

Theta Hat Statistical Consultants LLC.
3723 Birchmere Ct.
Owings Mills, MD  21117
Phone: 443-562-5952

bruce.thompson@thetahat.net

  • Home
  • Who are we?
  • Counting Processes
  • Survival Analysis
  • Longitudinal Data
  • Population Bioequivalence
  • Sample Size

Cumulative Event Curve Comparing Two Treatments

0      10      20      30      40      50      60      70      80  

Treatment One
Treatment Two

Time

  • A subject's baseline findings,
  • A subject's interim clinical findings,
  • Findings by treatment interactions, or
  • Simple changes in the event rate due to the passage of time

Treatment 
Placebo
Many clinical trial designs call for analyzing the time to first event but a subject can have multiple events over the course of the study.  By using counting processes, it is possible to model the event process and test whether the frequency of all events is the same  among the treatments.  This can increase the power of your analysis substantially.  This model can be extended to allow the event rate to change due to:

Counting Process Analysis